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Patients whose response to a treatment can be measured because enough information has been collected.
In cancer, the length of time after primary treatment for a cancer ends that the patient remains free of certain complications or events that the treatment was intended to prevent or delay. These events may include the return of the cancer or the onset of certain symptoms, such as bone pain from cancer that has spread to the bone. In a clinical trial, measuring the event-free survival is one way to see how well a new treatment works. Also called EFS.
A type of cancer that forms in bone or soft tissue. Also called peripheral primitive neuroectodermal tumor and PPNET.
Surgical removal of tissue.
A surgical procedure in which an entire lump or suspicious area is removed for diagnosis. The tissue is then examined under a microscope.
Medicine that makes mucous in your respiratory tract thinner and easier to cough out.
A substance that has been tested in the laboratory and has been approved by the U.S. Food and Drug Administration (FDA) for testing in people. Clinical trials test how well experimental drugs work and whether they are safe to use. An experimental drug may be approved by the FDA for use in one disease or condition but still be considered investigational in other diseases or conditions. Also called IND, investigational agent, investigational drug, and investigational new drug.
The group in a clinical research study that receives the drug, vaccine, or other intervention being tested. Interventions may also include medical procedures (such as radiation therapy and surgery), medical devices, behavior changes (such as diet and exercise), education programs, and counseling. Also called intervention group and investigational group.
Surgery undertaken to investigate a situation that other, primarily external diagnostic tests have failed to clarify.
A type of radiation therapy that uses a machine to aim high-energy rays at the cancer from outside of the body. Also called external radiation therapy.
