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Tacrolimus is a medicine that suppresses the immune system (immunosuppressant). It is used to decrease the body’s natural immune system response and prevent or treat GVHD after stem cell transplant. Tacrolimus may also be given after an organ transplant to prevent the immune system from attacking or rejecting the transplanted organ.
Your child may have a pharmacogenomic test to find out how their genes affect the way that they will use or respond to certain medicines. This can help your care team know the best dose of medicine for your child. Your doctor or pharmacist will let you know if your child needs a higher dose based on their genetic testing.
Your child will have regular blood draws to check potassium and magnesium levels in the blood and to monitor kidney and liver function.
Your care team will also measure tacrolimus levels in the blood. The dose may change based on these tests. Your care team will let you know when tests will be performed to measure tacrolimus levels in the blood. On the day of the test, your child should not take the medicine until after the blood sample is collected. If you have already taken tacrolimus before the lab is drawn, please tell your doctor or pharmacist.
May be given as a capsule by mouth
May be given as a liquid by mouth
May be given as a liquid into a vein by IV
May be applied on the skin
Not all patients who take tacrolimus will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist. Find more information on side effects.
Be sure to discuss all questions and instructions with your doctor or pharmacist.
This medicine can pose a health risk to caregivers or others who come in contact with the medicine. Follow instructions for safe handling, storage, and disposal. Keep all medicines out of the reach of children and pets.