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Often used for:
Brain tumors, Neuroblastoma, Ewing sarcoma, Rhabdomyosarcoma, Other solid tumors
Irinotecan is a type of chemotherapy. It works by stopping or slowing the growth cells. This medicine may be given in the clinic, hospital, or at home. The schedule and dose depends on the type of cancer, the child’s age, and method of administration.
Irinotecan by IV can cause tissue damage if it leaks from the vein. Patients may have irritation at the IV site. Let a caregiver know if there is burning during administration.
A genetic test may be performed to see how well the patient’s enzymes function. If a patient breaks down irinotecan more slowly, a lower dose of the medicine may be given.
Patients will have regular blood draws to check blood counts and monitor liver and kidney function.
May be taken as a liquid by mouth
May be given as a liquid into a vein by IV
Not all patients who take irinotecan will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.
Be sure to discuss these and other recommendations with your doctor or pharmacist.