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Adriamycin®, Doxil®, Lipodox 50
Liposomal doxorubicin, doxorubicin lipid complex, hydroxydaunomycin hydrochloride, doxorubicin hydrochloride
Often used for:
Leukemia, lymphoma, Wilms tumor, neuroblastoma, sarcomas, other solid tumors
Doxorubicin is a type of chemotherapy. It works by slowing or stopping the growth of cells. It is usually used in combination with other medicines.
Doxorubicin can cause serious heart problems. These problems can occur during therapy or months to years later. Tell your care team right away if your child has a cough, a heartbeat that is not normal (such as too fast or too slow), swelling in the arms or legs, shortness of breath, sudden weight gain, tiredness, or weakness. The care team may order tests before and during treatment to see if the heart is working well enough to receive doxorubicin. Your child may get a medicine called dexrazoxane to help prevent heart problems caused by doxorubicin.
Your child will have regular blood draws to check blood counts and liver and kidney function. This medicine can cause heart damage, so your child’s heart function will be closely monitored.
Doxorubicin can cause tissue damage or blisters if it leaks from the vein. Tell your care team if there is skin irritation or burning at the IV site.
Given as a liquid into a vein by IV or injection
Not all patients who take doxorubicin will have these side effects. Common side effects are in bold, but there may be others. Please report all symptoms or side effects to your doctor or pharmacist.
Doxorubicin may cause medical problems that continue or develop months or years after therapy ends. These may include:
Be sure to discuss all questions and instructions with your doctor or pharmacist.