Welcome to
Together is a new resource for anyone affected by pediatric cancer - patients and their parents, family members, and friends.
Learn MoreChemotherapy
Brand names:
Cytoxan®
Other names:
Cyclo, CPM, CTX
Often used for:
Leukemia, Lymphoma, Brain tumors, Sarcomas, Neuroblastoma, Retinoblastoma, Wilms tumor
Cyclophosphamide is a type of chemotherapy. It works by slowing or stopping the growth of cancer cells. It is usually used in combination with other drugs. It is also used to help prepare patients for hematopoietic cell transplant.
Cyclophosphamide can harm the kidneys and bladder. Patients receiving cyclophosphamide should drink plenty of fluids. They may receive IV fluids and a medicine called mesna to reduce the risk of bladder damage.
Patients will have regular blood draws to check blood counts and monitor liver and kidney function. In some cases, heart function may be assessed. Urine samples may be taken to check for blood in the urine.
May be taken as a tablet, capsule or liquid by mouth
May be given as a liquid into a vein by IV infusion
Not all patients who take cyclophosphamide will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.
Some patients may experience long-term or late effects of treatment that may continue or develop months or years after treatment ends. Possible late effects due to cyclophosphamide include:
Be sure to discuss these and other recommendations with your doctor or pharmacist.