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Anti-Inhibitor Coagulant Complex (FEIBA)

Supportive Care

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What is anti-inhibitor coagulant complex?

Anti-Inhibitor Coagulant Complex (also called Feiba VH®) is used to help manage bleeding disorders. It is available as a clear liquid given by vein (IV).

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Possible side effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Wheezing or cough
  • Shortness of breath
  • Flushing or dizziness
  • Fever or chills
  • Dark-colored urine
  • Black stool
  • Yellowing of skin or eyes
  • Nausea and vomiting
  • Redness, pain, or swelling where the needle was placed
  • Unusual bleeding, bruising, or weakness

Symptoms of an allergic reaction include: rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in the throat, swelling of the face or neck.

Not all patients who take anti-inhibitor coagulant complex will experience these side effects. Common side effects are bolded, but there may be others. Please report all suspected side effects to your doctor or pharmacist.

Find more information on side effects.

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Tips for patients and families

Be sure to discuss all questions and instructions with your doctor or pharmacist. 

  • Store this medicine in the refrigerator. Do not freeze it. It may also be stored at room temperature for up to 6 months. Be sure to write the date the product was placed at room temperature in the space provided on the outer carton.
  • Do not use this medicine after the expiration date.
  • You will be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection.
  • Try not to miss a dose. If possible, have other family members trained to give your treatment in case you cannot give it to yourself. If you miss a dose, ask your doctor, nurse, or pharmacist for instructions.
  • This medicine is a powder that must be mixed with sterile water before you use it.
    • The sterile water should come in the same package as the medicine.
    • Let both the powdered medicine and the sterile water warm to room temperature before mixing them together.
    • Swirl gently; do not shake vigorously.
  • If you cannot use the medicine right after mixing it, you can store it at room temperature. You must use the medicine within 3 hours of mixing.
  • Use a new needle and syringe each time you inject this medicine.
  • Throw away used needles in a patient sharps container (hard, closed container that needles cannot poke through). Keep this container away from children. Refer to handout called “Do you know… How to throw away sharp objects safely.”
  • Do not use the medicine after the expiration date has passed. Throw away medicine, containers, and other supplies in the trash after using them.
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Always check the medication label. Many medicines look the same. Do not take any new medicine, including over-the counter medicines or supplements, without checking with your doctor or pharmacist. Talk to your doctor or pharmacist about what to do in the case of a missed dose, allergic reaction, or medical emergency. 

This information is not intended to be a complete guide and is not a substitute for talking with your provider. Medicine names, appearance, formulas, or availability may vary by clinic location. Always follow the instructions given by your care team.

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