Together is a new resource for anyone affected by pediatric cancer - patients and their parents, family members, and friends.Learn More
trans-Retinoic Acid, retinoic acid
Often used for:
Acute promyelocytic leukemia (APL)
Tretinoin is a type of medicine called a retinoid. It acts on specific receptors of the cell nucleus to control cell growth. Tretinoin may be used as a chemotherapy to treat a type of leukemia called acute promyelocytic leukemia (APL).
When used as a chemotherapy, tretinoin is taken as a capsule by mouth. Tretinoin (as Retin-A®) may also be applied to the skin for treatment of acne or skin rashes.
Although retinoids are related to vitamin A (retinol), the actions are very different. It is important to follow the care team’s instructions and warnings when using a retinoid drug.
Female patients of childbearing age will be given a pregnancy test before starting tretinoin chemotherapy. Patients will have regular blood draws to monitor blood counts, lipid levels, and liver function.
May be taken as a capsule by mouth
May be applied on the skin
Possible side effects with lotion form:
Not all patients who take tretinoin will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.
Be sure to discuss these and other recommendations with your doctor or pharmacist.