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Often used for:
Graft vs. host disease (GVHD) after stem cell transplantation
Sirolimus is a medicine that suppresses the immune system (immunosuppressant). It is used to decrease the body’s natural immune system and prevent or treat GVHD in hematopoietic cell transplant. Sirolimus may also be used to prevent rejection of organ transplants.
Patients will have regular blood draws to check blood counts, cholesterol and triglyceride levels, and to monitor kidney and liver function. Sirolimus levels in the blood will be monitored, and doses may change based on levels in the blood.
May be taken as a tablet by mouth
May be taken as a liquid by mouth
Not all patients who take sirolimus will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.
Some patients may experience long-term or late effects of treatment that may continue or develop months or years after treatment ends. Possible late effects due to sirolimus include:
Be sure to discuss these and other recommendations with your doctor or pharmacist.