Skip to Main Content

Welcome to

Together is a new resource for anyone affected by pediatric cancer - patients and their parents, family members, and friends.

Learn More


Supportive Care

Brand names:

Oxaydo®, OxyContin®, Roxicodone®, Xtampza® ER

Other names:

Oxecta, Oxycodone HCl, Oxycodone Hydrochloride, RoxyBond

Often used for:


clipboard icon

About Oxycodone

Oxycodone is an opioid medicine used to control pain.

Oxycodone has fast-acting and slow-acting forms. Follow dosing instructions carefully. Families may be asked to keep a record of doses taken so the doctor can prescribe the best possible pain control.

Some products may use a combination of oxycodone and acetaminophen (Percocet®, Endocet®).

This drug may be habit-forming with long-term use.

A genetic test may be performed to see how well your enzymes function to determine how much oxycodone you should receive.

tablet and capsule icon

May be taken as a tablet by mouth

tablet and capsule icon

May be taken as a capsule by mouth

liquid dropper icon

May be taken as a liquid by mouth

exclamation mark in a circle icon

Possible Side Effects

  • Drowsiness
  • Nausea and vomiting
  • Constipation
  • Dizziness
  • Dry mouth
  • Slower than normal rates of breathing
  • Low blood pressure
  • Itching and hives
  • Mood changes (feeling sadder or happier than usual)
  • Fainting
  • Problems urinating

Not all patients who take oxycodone will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.

family icon

Tips for Families

Be sure to discuss these and other recommendations with your doctor or pharmacist.

  • If patients have any of the side effects listed above, most should decrease after taking oxycodone for a couple of days. Tell the doctor if the side effects increase while taking this medicine.
  • If taking this medicine regularly, patients should increase fluid and fiber intake to help prevent constipation. Tell the care team if the patient has not had a bowel movement in 3 to 5 days. Patients may need to take a stool softener or laxative to relieve constipation.
  • If patients are taking this medicine regularly or for a long time, they should not stop this medicine until the doctor instructs. Stopping oxycodone without slowly decreasing the dose can lead to diarrhea, headache, sweating, muscle cramps, trouble sleeping, nausea, vomiting, or feeling restless. If these symptoms occur, call the doctor right away. It could mean the dose is being decreased too fast.
  • Patients should tell their doctor if they are pregnant, attempting to get pregnant, or breastfeeding.

Oxycodone at home:

  • Do not take more often or in greater amounts than recommended.
  • This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you see how this medicine affects you.
  • Take oxycodone with food if stomach upset occurs.
  • Do not cut, chew, or crush the long-acting tablets. Swallow them whole.
  • The contents of the capsule can be sprinkled on a small amount of pudding, applesauce, or other soft food just before taking.
  • For liquid oxycodone, use the measuring device that comes with the medicine. Measure doses carefully.
  • If taking oxycodone with acetaminophen, do not take extra acetaminophen (Tylenol®) or medicines containing acetaminophen. This could result in a dose of acetaminophen that is too high.
  • Give a missed dose as soon as possible. If it is near the time of the next dose, skip the dose. Do not give 2 doses at the same time. 
  • Store at room temperature. Some formulations may need to be protected from light. Follow instructions from the pharmacy.
  • This drug may be habit-forming with long-term use. Watch for signs of misuse.
  • Do not share this medicine with anyone or give for reasons other than prescribed.
  • Do not use the medicine past the expiration date.
  • Follow instructions for safe storage and disposal.