Nelarabine

Chemotherapy

Brand names:

Arranon®

Often used for:

What is Nelarabine?

Nelarabine is a type of chemotherapy used to treat T-cell acute lymphoblastic leukemia (ALL) and T-cell lymphoblastic lymphoma. It works by slowing or stopping the growth of cells.

Patients will have regular blood draws to check blood counts and monitor liver and kidney function.

Given as a liquid into a vein by IV

Possible Side Effects

Low blood counts (may cause increased risk of infection, bleeding, anemia and/or fatigue)
Nausea or vomiting
Cough
Fatigue
Swelling or weight gain
Fever
Shortness of breath
Weakness
Peripheral neuropathy
Dizziness
Constipation
Diarrhea

Headache
Joint or muscle pain
Abdominal pain or swelling
Mouth sores
Loss of appetite
Problems sleeping
Blurry vision
Kidney problems
Liver problems
Seizures

Not all patients who take nelarabine will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.

Tips for Families

Be sure to discuss these and other recommendations with your doctor or pharmacist.

This medicine may cause drowsiness or dizziness. Patients should not drive or do anything that could be dangerous if they have these side effects.
While taking nelarabine, it is important to drink plenty of fluids. Patients should follow the care team’s instructions for appropriate fluid intake.
Sexually active patients should take steps to prevent pregnancy during treatment and for 3 months after completion of therapy.
Patients should tell their doctor if they are pregnant or breastfeeding.
Caregivers should follow instructions to avoid contact with patient body fluids which can contain the drug for several days after it is given.

Nelarabine resources

Learn More About Nelarabine

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Always check the medication label. Many medicines look the same. Do not take any new medicine, including over-the counter medicines or supplements, without checking with your doctor or pharmacist. Talk to your doctor or pharmacist about what to do in the case of a missed dose, allergic reaction, or medical emergency.

This information is not intended to be a complete guide and is not a substitute for talking with your provider. Medicine names, appearance, formulas, or availability may vary by clinic location. Always follow the instructions given by your care team.