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Phenylalanine Mustard; L-PAM; L-Phenylalanine Mustard; L-Sarcolysin
Often used for:
Multiple myeloma, Hodgkin lymphoma, Ovarian cancer, Conditioning for hematopoietic cell transplant
Melphalan is a type of chemotherapy. It works by slowing or stopping the growth of cancer cells. It may be used to help prepare patients for hematopoietic cell transplant.
Melphalan can cause tissue damage if it leaks from the vein. Patients may have irritation and skin damage at the IV site. Let a caregiver know if there is burning during administration.
Patients will have regular blood draws to check blood counts and monitor liver and kidney function.
May be taken as a tablet by mouth
May be given as a liquid into a vein by IV
Symptoms of an allergic reaction may include: hives, rash, itching, difficulty breathing and/or swallowing, low blood pressure
Not all patients who take melphalan will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.
Some patients may experience long-term or late effects of treatment that may continue or develop months or years after treatment ends. Possible late effects due to melphalan include:
Be sure to discuss these and other recommendations with your doctor or pharmacist.