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Leucovorin calcium, folinic acid
Often used for:
Side effects of high-dose Methotrexate in patients with leukemia, lymphoma, brain tumors, and osteosarcoma
Leucovorin helps to prevent some of the side effects caused by methotrexate. It acts to protect healthy cells from the chemotherapy.
Leucovorin usually does not cause any side effects. Rarely, a patient may have an allergic reaction to this medicine.
The dose and schedule is based on the child’s blood level of methotrexate. Leucovorin is generally given 24 to 42 hours after the start of methotrexate.
May be taken as a tablet or liquid by mouth
May be given as a liquid into a vein by IV
Be sure to discuss these and other recommendations with your doctor or pharmacist.