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Often used for:
Veno-occlusive disease of the liver (VOD; also known as hepatic sinusoidal obstruction syndrome or SOS)
Defibrotide (Defitelio®) is a medicine used to treat hepatic veno-occlusive disease (VOD). It works to help prevent or break down blood clots that can form in blood vessels of the liver.
Patients who have hematopoietic cell transplant (stem cell transplant) or certain chemotherapy medicines are at higher risk for VOD.
Defibrotide is usually given by IV every 6 hours for up to 60 days.
Given as a liquid that is injected into the veins (IV)
Not all patients who take defibrotide will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.
Be sure to discuss these and other recommendations with your doctor or pharmacist.