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Sucralfate

Supportive Care

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What is sucralfate?

Sucralfate (also called Carafate®) is used to treat ulcers. It coats the stomach lining and protects it from stomach acid and enzymes so healing can occur. Sucralfate is available as a light pink, oblong, 1-gm tablet and a pink liquid suspension. Both are taken by mouth.

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Possible side effects

  • Constipation
  • Gas
  • Stomach pain

    These are the most common side effects, but there may be others. Please report all side effects to the doctor or nurse.

Symptoms of an allergic reaction include: rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in the throat, swelling of the face or neck.

Not all patients who take sucralfate will experience these side effects. Common side effects are bolded, but there may be others. Please report all suspected side effects to your doctor or pharmacist.

Find more information on side effects.

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Tips for patients and families

Be sure to discuss all questions and instructions with your doctor or pharmacist. 

  • Take sucralfate 4 times a day, one (1) hour before each meal and at bedtime.
  • Take sucralfate on an empty stomach.
  • Sucralfate may affect the way other medicines work. These medicines include:
    • Cimetidine
    • Digoxin
    • Phenytoin
    • Ketoconazole
    • Itraconazole
    • Ciprofloxacin
    • Norfloxacin
    • Ranitidine
    • Sucralfate
    • Tetracycline
    • Theophylline
  • Always tell your doctor if you are taking any of these medicines, or if you start taking any new medicine while you are taking sucralfate.
  • Always take sucralfate 2 hours before or after you take any other medicine unless your doctor or pharmacist has told you otherwise.
  • Shake the liquid suspension very well before you take each dose.
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Always check the medication label. Many medicines look the same. Do not take any new medicine, including over-the counter medicines or supplements, without checking with your doctor or pharmacist. Talk to your doctor or pharmacist about what to do in the case of a missed dose, allergic reaction, or medical emergency. 

This information is not intended to be a complete guide and is not a substitute for talking with your provider. Medicine names, appearance, formulas, or availability may vary by clinic location. Always follow the instructions given by your care team.

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