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Erythropoietin

Supportive Care

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What is erythropoietin?

Erythropoietin (also called epoetin, Procrit®, or Epogen®) is used to prevent or treat anemia. It is a colorless liquid that is injected under the skin or given intravenously (IV, for chronic renal patients only). It is available in different strength vials:

  • 2,000 unit/ml vial
  • 4,000 unit/ml vial
  • 10,000 unit/ml vial
  • 20,000 unit/ml vial
  • 40,000 unit/ml vial
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Possible side effects

  • Pain, bruising, or swelling at the injection site (Sub-Q)
  • High blood pressure
  • Clots in the central line
  • Rash
  • Muscle aches and bone pain
  • Fatigue
  • Feeling dizzy
  • Headache

    These are the most common side effects, but there may be others. Please report all side effects to the doctor or nurse.

Symptoms of an allergic reaction include: rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in the throat, swelling of the face or neck.

Not all patients who take erythropoietin will experience these side effects. Common side effects are bolded, but there may be others. Please report all suspected side effects to your doctor or pharmacist.

Find more information on side effects.

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Tips for patients and families

Be sure to discuss all questions and instructions with your doctor or pharmacist. 

  • Your blood pressure will be checked routinely while you are receiving erythropoietin.
  • Keep the erythropoietin vials in the refrigerator (do not freeze). Place the vial at room temperature about an hour before the dose is due.
  • Do not shake the vial of erythropoietin.
  • If you have muscle aches or bone pain while you are receiving erythropoietin, ask your doctor if you may take acetaminophen (Tylenol®) to relieve the pain.

Drug at Home:

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Always check the medication label. Many medicines look the same. Do not take any new medicine, including over-the counter medicines or supplements, without checking with your doctor or pharmacist. Talk to your doctor or pharmacist about what to do in the case of a missed dose, allergic reaction, or medical emergency. 

This information is not intended to be a complete guide and is not a substitute for talking with your provider. Medicine names, appearance, formulas, or availability may vary by clinic location. Always follow the instructions given by your care team.

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