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Brand names:


Often used for:

Leukemia, Hodgkin lymphoma, lung cancer, solid tumors, brain tumors

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What is vinorelbine?

Vinorelbine is a type of chemotherapy. It works by slowing or stopping the growth of cells. It is usually used in combination with other medicines.

Your child will have regular blood draws to check blood counts and liver and kidney function.

Vinorelbine can cause tissue damage or blisters if it leaks from the vein. Tell your care team if there is skin irritation or burning at the IV site.


Given as a liquid into a vein by IV or injection 

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Possible side effects

  • Low blood counts (may cause increased risk of infection, bleeding, anemia, and fatigue)
  • Fatigue or weakness
  • Numbness or tingling in the hands or feet
  • Hair loss
  • Low platelets
  • Nausea 
  • Vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Bone or joint pain
  • Muscle pain or weakness
  • Fever
  • Abdominal (belly) pain
  • Loss of appetite
  • Skin irritation at the IV site
  • Liver problems
  • Mouth sores
  • Change in taste
  • Fertility problems in males (These may be temporary or long-term.)

Not all patients who take vinorelbine will have these side effects. Common side effects are in bold, but there may be others. Please report all symptoms or side effects to your doctor or pharmacist.

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Possible long-term or late effects

Some treatment may cause medical problems that continue or develop months or years after therapy ends. These may include: 

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Tips for patients and families

Be sure to discuss all questions and instructions with your doctor or pharmacist.

  • This medicine can weaken the immune system and increase the risk of infection. Wash hands often, keep patient areas clean, and avoid crowds or contact with people who are sick.
  • To help with constipation have your child drink plenty of fluids, exercise, and eat foods high in fiber. Your doctor may suggest a stool softener or laxative for constipation.
  • Your care team may prescribe medicine to reduce nausea and vomiting.
  • Your child may bleed more easily. Brush teeth gently with a soft toothbrush, use an electric razor to shave, and avoid activities that can cause injury.
  • Vinorelbine can affect your child’s ability to father a child. Talk to your doctor about the risk of fertility problems and options for protecting fertility.
  • This medicine can harm an unborn baby. Let your care team if your child is sexually active. Sexually active patients should take steps to prevent pregnancy during treatment and for 6 months after treatment is complete.
  • Tell your doctor if your child is pregnant or breastfeeding.
  • Take steps to protect caregivers and family members from drug hazards. Follow instructions for chemotherapy safety. Avoid contact with patient body fluids, which can contain the drug for 48 hours after it is given.