Together is a new resource for anyone affected by pediatric cancer - patients and their parents, family members, and friends.Learn More
Often used for:
Melanoma, Lung cancer
Trametinib (Mekinist®) is a type of medicine called a targeted therapy. This medicine is a MEK inhibitor. This medicine only works on cancer cells with a change or mutation in the MEK gene. Trametinib acts to block certain cell signals to help keep cells from growing. Before this medicine is given, patients will be tested to see if they have the BRAF V600 gene mutation.
Trametinib is used to treat melanoma and certain lung cancers. It is also being studied in other types of cancer. It may be used in combination with dabrafenib (Taflinar®).
Patients will have regular blood draws to check blood counts, glucose, and electrolyte levels in the blood and to monitor liver and kidney function. Patients will have regular skin and eye exams.
Given as a tablet by mouth
Other problems may occur when trametinib is given in combination with dabrafenib.
Not all patients who take trametinib will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.
Be sure to discuss these and other recommendations with your doctor or pharmacist.