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Glycopyrrolate

Anticholinergic Agent

Brand names:

Cuvposa®, Glycate®, Glyrx-PF®, Robinul®, Robinul-Forte®

Other names:

Glycopyrronium Bromide

Often used for:

Drooling, stomach ulcers

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What is glycopyrrolate?

Glycopyrrolate is a type of medicine called an anticholinergic. It is used to reduce bodily secretions such as saliva (drooling) and stomach acid.

This medicine may be given in the clinic, hospital or at home.

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May be given as a liquid by mouth

 
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May be given as a tablet by mouth

 
Injection icon

May be give as a shot into a muscle (intramuscular injection)

 
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May be given into a vein by IV

 
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Possible side effects

  • Vomiting
  • Dry mouth
  • Constipation
  • Trouble urinating (peeing)
  • Stuffy nose
  • Flushed skin or sudden redness in the face, neck, or chest
  • Headache
  • Sore throat, sneezing and cough
  • Sinus pain
  • Blurry vision or dry eyes
  • Reduced sweating
  • Allergic reaction – Call your care team right away if your child has symptoms of an allergic reaction. These may include:
    • Rash, hives, or itching
    • Flu-like symptoms such as chills, aches, headache, or fever 
    • Dizziness
    • Shortness of breath, coughing, or tightness in the throat  
    • Swelling of the face or neck

Not all patients who take glycopyrrolate will have these side effects. Common side effects are in bold, but there may be others. Report any symptoms or side effects to your health care provider or pharmacist. 

Find more information on side effects.

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Tips for patients and families

Be sure to discuss all questions and instructions with your health care provider or pharmacist. 

  • This medicine can cause constipation. To help with constipation have your child drink plenty of fluids, exercise, and eat foods high in fiber.
  • Let your care team know if your child has a decrease in urine (pee) or severe diarrhea. 
  • This medicine may cause drowsiness or blurry vision. Do not let your child do anything that could be dangerous until you see how this medicine affects them.
  • Bright lights may bother your child. Have your child wear sunglasses.
  • This medicine may reduce your child’s ability to sweat and regulate body temperature (cool the body). Talk to your care team about precautions needed during hot weather or during physical activity.
  • It is important that patients tell the care team if they are sexually active, pregnant, or breastfeeding.  

Glycopyrrolate at home

  • Give this medicine as ordered by your child's health care team. Read all information given to you. Follow all instructions closely.
  • Tablet: This medicine can be taken with or without food. Take with food if stomach upset occurs. Taking the medicine with meals may lessen stomach problems
  • Liquid: Take medicine on an empty stomach. Use the measuring device that comes with the medicine.
  • Keep giving this medicine to your child as you have been told by your child’s health care provider, even if your child feels well.
  • In case of a missed dose, give the missed dose as soon as possible. If it is near the time for the next dose, skip the missed dose. Do not give 2 doses at the same time.
  • Store at room temperature in a dry place.
  • Do not use the medicine past the expiration date.

Learn more about glycopyrrolate

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Always check the medication label. Many medicines look the same. Do not take any new medicine, including over-the counter medicines or supplements, without checking with your doctor or pharmacist. Talk to your doctor or pharmacist about what to do in the case of a missed dose, allergic reaction, or medical emergency. 

This information is not intended to be a complete guide and is not a substitute for talking with your provider. Medicine names, appearance, formulas, or availability may vary by clinic location. Always follow the instructions given by your care team.

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Reviewed: July 2024