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Dexrazoxane

Supportive Care

Brand names:

Totect®, Zinecard®

Often used for:

Heart problems or tissue damage caused by other medicines

What is Dexrazoxane?

Dexrazoxane is a medicine used to prevent damage to the heart caused by certain cancer medicines such as doxorubicin. It can also help treat tissue damage caused by some medicines if they leak out of a vein when they are given.

Given as a liquid into a vein by IV or injection

Possible Side Effects

Pain or irritation where the shot was given
Low blood counts
Fatigue or weakness
Nausea or vomiting
Stomach pain
Loss of appetite
Diarrhea
Constipation
Hair loss
Headache
Trouble sleeping
Fever
Increased risk of infection
Loss of fertility in males

Symptoms of an allergic reaction include: rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in the throat, swelling of the face or neck.

Not all patients who take DRUG will experience these side effects. Common side effects are bolded, but there may be others. Please report all suspected side effects to your doctor or pharmacist.

Tips for Families

Be sure to discuss these and other recommendations with your doctor or pharmacist.

Tell your doctor if your child is using a medicine on the skin called dimethyl sulfoxide (DMSO).
Sexually active patients should take steps to prevent pregnancy during and after treatment as recommended by their doctor.
Patients should tell their doctor if they are pregnant or breastfeeding.

Learn More About Dexrazoxane

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Always check the medication label. Many medicines look the same. Do not take any new medicine, including over-the counter medicines or supplements, without checking with your doctor or pharmacist. Talk to your doctor or pharmacist about what to do in the case of a missed dose, allergic reaction, or medical emergency.

This information is not intended to be a complete guide and is not a substitute for talking with your provider. Medicine names, appearance, formulas, or availability may vary by clinic location. Always follow the instructions given by your care team.