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Learn MoreChemotherapy
Brand names:
DTIC-Dome®
Other names:
Dimethyl Triazeno Imidazol Carboxamide, Imidazole Carboxamide, DIC, DTIC
Often used for:
Treatment of malignant melanoma, Hodgkin lymphoma, soft tissue sarcomas, islet cell carcinoma, pheochromocytoma, medullary carcinoma of the thyroid
Dacarbazine is a type of chemotherapy. It is used to treat Hodgkin lymphoma and melanoma that has spread to other parts of the body. It also can be used to treat other forms of cancer. It works by slowing or stopping the growth of cancer cells in the body.
This medicine may be given in a clinic or hospital.
Your child will have regular blood tests to check how their body responds to the medicine. Patients may get another medicine to reduce nausea.
This medicine can cause severe side effects. These include liver damage, birth defects, and reducing the number of blood cells in the bone marrow. Talk to your doctor about risks of using dacarbazine.
Dacarbazine can cause tissue damage, blisters, or skin irritation if it leaks from the vein. Tell your care team if your child has pain, burning, redness, or swelling around the IV site.
May be given into a vein by IV
Some people have severe side effects after receiving dacarbazine. Contact your child’s health care team right away if your child has any of the following:
Not all patients who take dacarbazine will have these side effects. Common side effects are in bold, but there may be others. Report any symptoms or side effects to your provider or pharmacist. Find more information on side effects.
Your care team can give you more information about your child’s risk.
Be sure to discuss all questions and instructions with your doctor or pharmacist.