Skip to Main Content

Welcome to

Together is a new resource for anyone affected by pediatric cancer - patients and their parents, family members, and friends.

Learn More
Blog

Cladribine

Chemotherapy

clipboard icon

What is cladribine?

Cladribine (also known as 2-CDA or Leustatin®) is an anticancer medicine. It is a clear liquid given into a vein (IV).

Cladribine can pose a health hazard to caregivers. All caregivers should take safety precautions while giving this drug. For 48 hours after this drug is given, the patient’s body fluids can contain the drug. During that 48-hour period, caregivers should follow safety guidelines when handling the patient’s vomit, blood, urine, and bowel movements, including diapers. These guidelines include wearing gloves when cleaning up body fluids. For a complete list of safety precautions, see “Do you know… Protecting caregivers from drug hazards.”

exclamation mark in a circle icon

Possible side effects

  • Nausea
  • Rash and itching

Symptoms of an allergic reaction include: rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in the throat, swelling of the face or neck.

Not all patients who take cladribine will experience these side effects. Common side effects are bolded, but there may be others. Please report all suspected side effects to your doctor or pharmacist.

Find more information on side effects.

late effects icon

Possible late effects

  • Fever
  • Lower blood counts 10 to 14 days later
  • Decreased kidney and liver function
family icon

Tips for patients and families

Be sure to discuss all questions and instructions with your doctor or pharmacist. 

  • It may be easier for you to get infections while you are receiving cladribine. Stay away from crowds and people with colds, flu, or other infections.
  • Cladribine can cause nausea and vomiting. The doctor may prescribe medicine to keep you from feeling sick and throwing up after you receive cladribine.