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Amitriptyline

Antidepressant

Brand names:

Elavil®

Often used for:

Depression, Headache prevention, Nerve pain, Sleep problems

About Amitriptyline

Amitriptyline is an antidepressant drug. It is sometimes used for headache prevention, to treat nerve pain, or to help with sleep problems.

Antidepressant medications may increase suicidal thoughts or actions in some children and young adults within the first few months of treatment. Call the healthcare provider to report new or sudden changes in mood, behavior, thoughts or feelings.

May be taken as a tablet by mouth

Possible Side Effects

Feeling more tired than usual
Vision problems (dry eyes, blurry vision, or eye pain)
Dry mouth
Feeling drowsy, dizzy, or unsteady
Nausea and vomiting
Constipation or diarrhea
Change in how much or how often you urinate
Agitation, nervousness, irritability
Headaches
Skin irritation, rash

Skin more sensitive to the sun
Weight gain or loss
Fever with increased sweating
Changes in blood sugar levels
Hallucinations
Seizure
Low blood pressure
Irregular or fast heartbeat

Not all patients who take amitriptyline will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.

Tips for Families

Be sure to discuss these and other recommendations with your doctor or pharmacist.

If taking amitriptyline for depression, it may take several weeks for the medicine to start working.
If taking amitriptyline for nerve pain, the medicine should begin to work within 5 to 7 days.
Patients should tell their doctor if they are pregnant, trying to get pregnant, or breastfeeding.

Amitriptyline at home:

This medicine may make you dizzy or drowsy and can increase the risk of falls. Do not drive or do anything that could be dangerous until you see how this medicine affects you.
Most often, amitriptyline is taken one (1) time a day. Taking this medicine at bedtime may keep patients from feeling sleepy during the day. If you have trouble sleeping while taking amitriptyline, then take it in the morning.
In case of a missed dose, give the missed dose as soon as possible. If it is near the time for the next dose, skip the dose. Do not take extra medicine to make up for a missed dose.
Do not stop taking this medication without first talking to your healthcare provider. Stopping amitriptyline too quickly may cause these symptoms: nausea, headache, feeling more tired than usual, dizzy feeling, and feeling irritable.
Store this medicine at room temperature in a dry place.
Always tell your doctor what medicines you are on and if you start taking any new medicines while taking amitriptyline.
Finish all doses of the medicine as instructed by a doctor.
Do not use the medicine past the expiration date.
Follow instructions for safe storage and disposal.

Learn More About Amitriptyline

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Always check the medication label. Many medicines look the same. Do not take any new medicine, including over-the counter medicines or supplements, without checking with your doctor or pharmacist. Talk to your doctor or pharmacist about what to do in the case of a missed dose, allergic reaction, or medical emergency.

This information is not intended to be a complete guide and is not a substitute for talking with your provider. Medicine names, appearance, formulas, or availability may vary by clinic location. Always follow the instructions given by your care team.