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Clarithromycin

Antibiotic

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What is clarithromycin?

Clarithromycin (also called Biaxin®) is used to prevent or treat infections. It is available in the following strengths; all are taken by mouth:

  • a 250 mg tablet
  • a 500 mg tablet
  • a 500 mg (XL) extended-release tablet
  • a 25 mg/mL liquid suspension
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Possible side effects

  • Nausea, vomiting
  • Diarrhea
  • Rash
  • Changed taste
  • Headache
  • Stomach pain
  • Indigestion

    These are the most common side effects, but there may be others. Please report all side effects to the doctor or nurse.

Symptoms of an allergic reaction include: rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in the throat, swelling of the face or neck.

Not all patients who take clarithromycin will experience these side effects. Common side effects are bolded, but there may be others. Please report all suspected side effects to your doctor or pharmacist.

Find more information on side effects.

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Tips for patients and families

Be sure to discuss all questions and instructions with your doctor or pharmacist. 

  • You may take all forms of clarithromycin except the extended-release (XL) tablets with or without food. If you have stomach pain, take clarithromycin with food.
  • The clarithromycin extended-release tablets (XL) are taken one time a day with food.
  • Store all tablets at room temperature in dry place.
  • Shake the liquid well before you take it. Use an oral syringe or medicine cup to be sure you are taking the correct amount.
  • Store the liquid medicine at room temperature. Do not refrigerate.
  • Discard the liquid medicine after 14 days or on the expiration date printed on the label.

Drug at Home:

  • You may take all forms of clarithromycin except the extended-release (XL) tablets with or without food. If you have stomach pain, take clarithromycin with food.
  • The clarithromycin extended-release tablets (XL) are taken one time a day with food.
  • Store all tablets at room temperature in dry place.
  • Shake the liquid well before you take it. Use an oral syringe or medicine cup to be sure you are taking the correct amount.
  • Store the liquid medicine at room temperature. Do not refrigerate.
  • Discard the liquid medicine after 14 days or on the expiration date printed on the label.
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Always check the medication label. Many medicines look the same. Do not take any new medicine, including over-the counter medicines or supplements, without checking with your doctor or pharmacist. Talk to your doctor or pharmacist about what to do in the case of a missed dose, allergic reaction, or medical emergency. 

This information is not intended to be a complete guide and is not a substitute for talking with your provider. Medicine names, appearance, formulas, or availability may vary by clinic location. Always follow the instructions given by your care team.

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